Nivolumab for Patients With Advanced Melanoma Treated Beyond Progression: Analysis of 2 Phase 3 Clinical Trials.
Identifieur interne : 000726 ( Main/Exploration ); précédent : 000725; suivant : 000727Nivolumab for Patients With Advanced Melanoma Treated Beyond Progression: Analysis of 2 Phase 3 Clinical Trials.
Auteurs : Georgina V. Long [Australie] ; Jeffrey S. Weber [États-Unis] ; James Larkin [Royaume-Uni] ; Victoria Atkinson [Australie] ; Jean-Jacques Grob [France] ; Dirk Schadendorf [Allemagne] ; Reinhard Dummer [Suisse] ; Caroline Robert [France] ; Ivan Márquez-Rodas [Espagne] ; Catriona Mcneil [Australie] ; Henrik Schmidt [Danemark] ; Karen Briscoe [Australie] ; Jean-François Baurain [Belgique] ; F Stephen Hodi [États-Unis] ; Jedd D. Wolchok [États-Unis]Source :
- JAMA oncology [ 2374-2445 ] ; 2017.
Abstract
Immune checkpoint inhibitors have demonstrated atypical response patterns, which may not be fully captured by conventional response criteria. There is a need to better understand the potential benefit of continued immune checkpoint inhibition beyond progression.
DOI: 10.1001/jamaoncol.2017.1588
PubMed: 28662232
Affiliations:
- Allemagne, Australie, Belgique, Danemark, Espagne, France, Royaume-Uni, Suisse, États-Unis
- Angleterre, Communauté de Madrid, Floride, Grand Londres, Massachusetts, Nouvelle-Galles du Sud, Provence-Alpes-Côte d'Azur, Région de Bruxelles-Capitale, État de New York
- Bruxelles, Londres, Madrid, Marseille, Sydney
- Université de Sydney
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000205
- to stream PubMed, to step Curation: 000205
- to stream PubMed, to step Checkpoint: 000205
- to stream Ncbi, to step Merge: 004A55
- to stream Ncbi, to step Curation: 004A55
- to stream Ncbi, to step Checkpoint: 004A55
- to stream Main, to step Merge: 000721
- to stream Main, to step Curation: 000726
Le document en format XML
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last="Márquez-Rodas">Ivan Márquez-Rodas</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Mcneil, Catriona" sort="Mcneil, Catriona" uniqKey="Mcneil C" first="Catriona" last="Mcneil">Catriona Mcneil</name><affiliation wicri:level="1"><nlm:affiliation>Chris O'Brien Lifehouse, Melanoma Institute Australia, Camperdown, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Chris O'Brien Lifehouse, Melanoma Institute Australia, Camperdown, New South Wales</wicri:regionArea><wicri:noRegion>New South 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Long</name><affiliation wicri:level="4"><nlm:affiliation>Melanoma Institute Australia, University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Melanoma Institute Australia, University of Sydney, Sydney, New South Wales</wicri:regionArea><orgName type="university">Université de Sydney</orgName><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Weber, Jeffrey S" sort="Weber, Jeffrey S" uniqKey="Weber J" first="Jeffrey S" last="Weber">Jeffrey S. Weber</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medical Oncology, Moffitt Cancer Center, Tampa, Florida.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Department of Medical Oncology, Moffitt Cancer Center, Tampa</wicri:cityArea></affiliation></author><author><name sortKey="Larkin, James" sort="Larkin, James" uniqKey="Larkin J" first="James" last="Larkin">James Larkin</name><affiliation wicri:level="3"><nlm:affiliation>Department of Oncology, Royal Marsden Hospital, London, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Oncology, Royal Marsden Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Atkinson, Victoria" sort="Atkinson, Victoria" uniqKey="Atkinson V" first="Victoria" last="Atkinson">Victoria Atkinson</name><affiliation wicri:level="1"><nlm:affiliation>Gallipoli Medical Research Foundation and Princess Alexandra Hospital, and University of Queensland, Queensland, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Gallipoli Medical Research Foundation and Princess Alexandra Hospital, and University of Queensland, Queensland</wicri:regionArea><wicri:noRegion>Queensland</wicri:noRegion></affiliation></author><author><name sortKey="Grob, Jean Jacques" sort="Grob, Jean Jacques" uniqKey="Grob J" first="Jean-Jacques" last="Grob">Jean-Jacques Grob</name><affiliation wicri:level="3"><nlm:affiliation>Department of Dermatology and Skin Cancer, Hospital Timone APHM, Aix-Marseille University, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Dermatology and Skin Cancer, Hospital Timone APHM, Aix-Marseille University, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Schadendorf, Dirk" sort="Schadendorf, Dirk" uniqKey="Schadendorf D" first="Dirk" last="Schadendorf">Dirk Schadendorf</name><affiliation wicri:level="1"><nlm:affiliation>Department of Skin, University Hospital Essen, Essen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Skin, University Hospital Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Dummer, Reinhard" sort="Dummer, Reinhard" uniqKey="Dummer R" first="Reinhard" last="Dummer">Reinhard Dummer</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, UniversitaetsSpital, Zurich, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Dermatology, UniversitaetsSpital, Zurich</wicri:regionArea><wicri:noRegion>Zurich</wicri:noRegion></affiliation></author><author><name sortKey="Robert, Caroline" sort="Robert, Caroline" uniqKey="Robert C" first="Caroline" last="Robert">Caroline Robert</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine Institute Gustave Roussy, Gustave Roussy and Paris-Sud University, Villejuif Paris-Sud, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Medicine Institute Gustave Roussy, Gustave Roussy and Paris-Sud University, Villejuif Paris-Sud</wicri:regionArea><wicri:noRegion>Villejuif Paris-Sud</wicri:noRegion><wicri:noRegion>Villejuif Paris-Sud</wicri:noRegion></affiliation></author><author><name sortKey="Marquez Rodas, Ivan" sort="Marquez Rodas, Ivan" uniqKey="Marquez Rodas I" first="Ivan" last="Márquez-Rodas">Ivan Márquez-Rodas</name><affiliation wicri:level="3"><nlm:affiliation>Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Servicio de Oncología Médica, Hospital General Universitario Gregorio Marañón, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Mcneil, Catriona" sort="Mcneil, Catriona" uniqKey="Mcneil C" first="Catriona" last="Mcneil">Catriona Mcneil</name><affiliation wicri:level="1"><nlm:affiliation>Chris O'Brien Lifehouse, Melanoma Institute Australia, Camperdown, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Chris O'Brien Lifehouse, Melanoma Institute Australia, Camperdown, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Schmidt, Henrik" sort="Schmidt, Henrik" uniqKey="Schmidt H" first="Henrik" last="Schmidt">Henrik Schmidt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Oncology, Aarhus University Hospital, Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Department of Oncology, Aarhus University Hospital, Aarhus</wicri:regionArea><wicri:noRegion>Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Briscoe, Karen" sort="Briscoe, Karen" uniqKey="Briscoe K" first="Karen" last="Briscoe">Karen Briscoe</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Oncology, Coffs Harbour Health Campus, New South Wales, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Department of Medical Oncology, Coffs Harbour Health Campus, New South Wales</wicri:regionArea><wicri:noRegion>New South Wales</wicri:noRegion></affiliation></author><author><name sortKey="Baurain, Jean Francois" sort="Baurain, Jean Francois" uniqKey="Baurain J" first="Jean-François" last="Baurain">Jean-François Baurain</name><affiliation wicri:level="3"><nlm:affiliation>Melanoma Clinic at King Albert II Cancer Institute, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Bruxelles, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Melanoma Clinic at King Albert II Cancer Institute, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Bruxelles</wicri:regionArea><placeName><settlement type="city">Bruxelles</settlement><region nuts="2">Région de Bruxelles-Capitale</region></placeName></affiliation></author><author><name sortKey="Hodi, F Stephen" sort="Hodi, F Stephen" uniqKey="Hodi F" first="F Stephen" last="Hodi">F Stephen Hodi</name><affiliation wicri:level="2"><nlm:affiliation>Melanoma Center and Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Melanoma Center and Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Wolchok, Jedd D" sort="Wolchok, Jedd D" uniqKey="Wolchok J" first="Jedd D" last="Wolchok">Jedd D. Wolchok</name><affiliation wicri:level="2"><nlm:affiliation>Ludwig Center for Cancer Immunotherapy at Memorial Sloan Kettering Cancer Center, New York, New York.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Ludwig Center for Cancer Immunotherapy at Memorial Sloan Kettering Cancer Center, New York</wicri:cityArea></affiliation></author></analytic><series><title level="j">JAMA oncology</title><idno type="eISSN">2374-2445</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Immune checkpoint inhibitors have demonstrated atypical response patterns, which may not be fully captured by conventional response criteria. There is a need to better understand the potential benefit of continued immune checkpoint inhibition beyond progression.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Danemark</li><li>Espagne</li><li>France</li><li>Royaume-Uni</li><li>Suisse</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Communauté de Madrid</li><li>Floride</li><li>Grand Londres</li><li>Massachusetts</li><li>Nouvelle-Galles du Sud</li><li>Provence-Alpes-Côte d'Azur</li><li>Région de Bruxelles-Capitale</li><li>État de New York</li></region><settlement><li>Bruxelles</li><li>Londres</li><li>Madrid</li><li>Marseille</li><li>Sydney</li></settlement><orgName><li>Université de Sydney</li></orgName></list><tree><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Long, Georgina V" sort="Long, Georgina V" uniqKey="Long G" first="Georgina V" last="Long">Georgina V. Long</name></region><name sortKey="Atkinson, Victoria" sort="Atkinson, Victoria" uniqKey="Atkinson V" first="Victoria" last="Atkinson">Victoria Atkinson</name><name sortKey="Briscoe, Karen" sort="Briscoe, Karen" uniqKey="Briscoe K" first="Karen" last="Briscoe">Karen Briscoe</name><name sortKey="Mcneil, Catriona" sort="Mcneil, Catriona" uniqKey="Mcneil C" first="Catriona" last="Mcneil">Catriona Mcneil</name></country><country name="États-Unis"><region name="Floride"><name sortKey="Weber, Jeffrey S" sort="Weber, Jeffrey S" uniqKey="Weber J" first="Jeffrey S" last="Weber">Jeffrey S. Weber</name></region><name sortKey="Hodi, F Stephen" sort="Hodi, F Stephen" uniqKey="Hodi F" first="F Stephen" last="Hodi">F Stephen Hodi</name><name sortKey="Wolchok, Jedd D" sort="Wolchok, Jedd D" uniqKey="Wolchok J" first="Jedd D" last="Wolchok">Jedd D. Wolchok</name></country><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Larkin, James" sort="Larkin, James" uniqKey="Larkin J" first="James" last="Larkin">James Larkin</name></region></country><country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Grob, Jean Jacques" sort="Grob, Jean Jacques" uniqKey="Grob J" first="Jean-Jacques" last="Grob">Jean-Jacques Grob</name></region><name sortKey="Robert, Caroline" sort="Robert, Caroline" uniqKey="Robert C" first="Caroline" last="Robert">Caroline Robert</name></country><country name="Allemagne"><noRegion><name sortKey="Schadendorf, Dirk" sort="Schadendorf, Dirk" uniqKey="Schadendorf D" first="Dirk" last="Schadendorf">Dirk Schadendorf</name></noRegion></country><country name="Suisse"><noRegion><name sortKey="Dummer, Reinhard" sort="Dummer, Reinhard" uniqKey="Dummer R" first="Reinhard" last="Dummer">Reinhard Dummer</name></noRegion></country><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Marquez Rodas, Ivan" sort="Marquez Rodas, Ivan" uniqKey="Marquez Rodas I" first="Ivan" last="Márquez-Rodas">Ivan Márquez-Rodas</name></region></country><country name="Danemark"><noRegion><name sortKey="Schmidt, Henrik" sort="Schmidt, Henrik" uniqKey="Schmidt H" first="Henrik" last="Schmidt">Henrik Schmidt</name></noRegion></country><country name="Belgique"><region name="Région de Bruxelles-Capitale"><name sortKey="Baurain, Jean Francois" sort="Baurain, Jean Francois" uniqKey="Baurain J" first="Jean-François" last="Baurain">Jean-François Baurain</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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